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MUTED Antibody - C-terminal region: Biotin (ARP63302_P050-Biotin)

Product Specifications

Gene Aliases

MU, BLOS5, HPS11, MUTED

Gene ID

63915

Swiss Prot

Q8TDH9

Accession Number

NP_958437

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of MUTED

Target

This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1) . Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.

Partner Proteins

HUWE1; TSNAX; UBC; APP; DCUN1D1; SQSTM1; YOD1; BLOC1S2; BLOC1S4; DTNBP1; SNAPIN; BLOC1S1; BLOC1S6; BLOC1S3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

Shipping Conditions

Wet Ice

Protein Length

187

NCBI Gene Symbol

BLOC1S5

Protein Name

Biogenesis of lysosome-related organelles complex 1 subunit 5

Nucleotide Accession Number

NM_201280

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