NRAS Antibody - middle region : FITC (ARP63292_P050-FITC)

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

UBC; MDM2; RGL2; VAT1; RNASEH2B; SPATS2; CD2AP; ELAVL1; SRI; RPS20; DNAJB1; EEF1A1; RAP1GDS1; RASGRP2; PLCE1; SMURF2; RASSF5; RACGAP1; SHOC2; SMAD4; ARHGAP4; PIK3CA; RAF1; BCL2; ACVR1; PIK3CG; MLLT4

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.