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AICDA Antibody : FITC (ARP63254_P050-FITC)

Product Specifications

Gene Name

Activation-induced cytidine deaminase

Gene Aliases

AID, ARP2, CDA2, HIGM2, HEL-S-284

Gene ID

57379

Swiss Prot

Q9GZX7

Accession Number

NP_065712

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence VKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFT

Target

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) .

Partner Proteins

PGAM1; HNRNPM; KPNB1; HSPA5; FEN1; EIF2D; EEF1A1; ACTG1; ZMIZ2; HERPUD2; AICDA; CTNNBL1; RNF126; HAUS4; CPSF3; RTCB; IER5; RRM2B; XRN2; DDX19B; HNRNPA0; CCT7; DAZAP2; NUP93; RBM39; DDX21; UBE2L3; UBC; RPA1; RAD51; PPP2R1A; EXOSC6; EXOSC5; EXOSC4; EXOSC1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

24 kDa

Shipping Conditions

Wet Ice

Protein Length

198

NCBI Gene Symbol

AICDA

NCBI GB Accession Number

AICDA

Host or Source

Rabbit

Protein Name

Activation-induced cytidine deaminase

Nucleotide Accession Number

NM_020661

Peptide Sequence

VKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFT

Frequently Asked Questions

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