AICDA Antibody: Biotin (ARP63254_P050-Biotin)
Product Specifications
Gene Name
Activation-induced cytidine deaminase
Gene Aliases
AID, ARP2, CDA2, HIGM2, HEL-S-284
Gene ID
57379
Swiss Prot
Q9GZX7
Accession Number
NP_065712
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence VKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFT
Target
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) .
Partner Proteins
PGAM1; HNRNPM; KPNB1; HSPA5; FEN1; EIF2D; EEF1A1; ACTG1; ZMIZ2; HERPUD2; AICDA; CTNNBL1; RNF126; HAUS4; CPSF3; RTCB; IER5; RRM2B; XRN2; DDX19B; HNRNPA0; CCT7; DAZAP2; NUP93; RBM39; DDX21; UBE2L3; UBC; RPA1; RAD51; PPP2R1A; EXOSC6; EXOSC5; EXOSC4; EXOSC1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24 kDa
Shipping Conditions
Wet Ice
Protein Length
198
NCBI Gene Symbol
AICDA
Protein Name
Activation-induced cytidine deaminase
Nucleotide Accession Number
NM_020661
Curated Selection
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