PDE5A Antibody - C-terminal region : Biotin (ARP63250_P050-Biotin)
Selected Variant
ARP63250_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Phosphodiesterase 5A, cGMP-specific
Gene Aliases
CN5A, PDE5, CGB-PDE
Gene ID
8654
Swiss Prot
O76074
Accession Number
NP_246273
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Partner Proteins
UBC; PRKG1; CASP3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
93kDa
Shipping Conditions
Wet Ice
Protein Length
823
NCBI Gene Symbol
PDE5A
NCBI GB Accession Number
PDE5A
Host or Source
Rabbit
Protein Name
CGMP-specific 3',5'-cyclic phosphodiesterase
Nucleotide Accession Number
NM_033437
Peptide Sequence
TACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKK
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