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CTSL1 Antibody - C-terminal region : FITC (ARP63239_P050-FITC)

Selected Variant

ARP63239_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Cathepsin L1

Gene Aliases

MEP, CATL, CTSL1

Gene ID

1514

Swiss Prot

P07711

Accession Number

NP_666023

Host

Rabbit

Reactivity

Human, Mouse, Rat, Sheep

Target

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Partner Proteins

SGTA; SERPINB3; BTN3A3; RELB; PPP1CC; APOA1; ALB; UBC; EED; BAG6; GEM; ARSA; SERPINB13; CST3; CST7; CTSC; CSTB; KNG1; PLAU; TG; CD7; CSTA; RXRA; CXCL8; IGFBP3; CD74; GCG; COL18A1; CUX1; CTSL; SLPI

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 77%; Rat: 77%; Sheep: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

Shipping Conditions

Wet Ice

Protein Length

333

NCBI Gene Symbol

CTSL

NCBI GB Accession Number

CTSL

Host or Source

Rabbit

Protein Name

Cathepsin L1

Nucleotide Accession Number

NM_145918

Peptide Sequence

GGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVG

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