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HLA-G Antibody - C-terminal region : Biotin (ARP63107_P050-Biotin)

Product Specifications

Gene Name

Major histocompatibility complex, class I, G

Gene Aliases

MHC-G

Gene ID

3135

Swiss Prot

P17693

Accession Number

NP_002118

Host

Rabbit

Reactivity

Human, Cow, Pig

Target

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

Partner Proteins

UBC; FAF2; KIR2DL4; LILRB2; LILRB1; KLRD1; COPB1; CD8A; TAP2; TAP1; HLA-G; B2M

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HLA-G is strongly supported by BioGPS gene expression data to be expressed in RPMI-8226

Concentration

0.5 mg/ml

Homology

Cow: 93%; Human: 100%; Pig: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-HLA-G (ARP63107_P050-Biotin) antibody

Protein Length

338

NCBI Gene Symbol

HLA-G

NCBI GB Accession Number

HLA-G

Host or Source

Rabbit

Protein Name

HLA class I histocompatibility antigen, alpha chain G

Nucleotide Accession Number

NM_002127

Peptide Sequence

HPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGTF

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