L1CAM Antibody - C-terminal region : FITC (ARP63103_P050-FITC)

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

RANBP9; FBXO6; NRP1; Caskin1; RABGEF1; UBC; EZR; CANX; CNTN1; NUMB; PEA15; RPS6KA2; RPS6KA1; NCAN; MSN; ITGAV; CNTN2; ANK1; RDX; PRNP; ITGA5; NCAM1; CSNK2A1; ANK2; AP2A1; AP2M1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.