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TFPI Antibody - middle region : FITC (ARP63092_P050-FITC)

Selected Variant

ARP63092_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

Gene Aliases

EPI, TFI, LACI, TFPI1

Gene ID

7035

Swiss Prot

P10646

Accession Number

NP_006278

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

This gene encodes a protease inhibitor that regulates the tissue factor (TF) -dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Partner Proteins

SMU1; SF3B1; BCAS2; SAP18; SRSF11; SON; SRSF7; APP; ELAVL1; PRSS3; MMP12; F10; THBS1; MMP7; ELANE; MMP9; MMP8; MMP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 77%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

Shipping Conditions

Wet Ice

Protein Length

304

NCBI Gene Symbol

TFPI

NCBI GB Accession Number

TFPI

Host or Source

Rabbit

Protein Name

Tissue factor pathway inhibitor

Nucleotide Accession Number

NM_006287

Peptide Sequence

QEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETL

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