MCC Antibody - C-terminal region: FITC (ARP63047_P050-FITC)
Product Specifications
Gene Name
Mutated in colorectal cancers
Gene Aliases
MCC1
Gene ID
4163
Swiss Prot
P23508-2
Accession Number
NP_002378
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse
Target
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
CSNK1E; ERBB2IP; CBX5; GTF2E2; APP; DYNC1I1; NEK2; NFKBIB; STRIP1; VPS35; STRN3; STRN4; SNRNP200; PDCD10; PAICS; PSME3; CCNA1; EIF3A; STK24; EZR; VHL; VDAC1; VCP; TPM3; TARS; STRN; PSMD2; PPP2R1A; PFKP; PFAS; MYH10; MTHFD1; MARS; LTA4H; KRT18; IARS; HPRT1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 79%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
91kDa
Shipping Conditions
Wet Ice
Protein Length
829
NCBI Gene Symbol
MCC
Protein Name
Colorectal mutant cancer protein
Nucleotide Accession Number
NM_002387
Curated Selection
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