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MRPS18B Antibody - N-terminal region : FITC (ARP62873_P050-FITC)

Selected Variant

ARP62873_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Mitochondrial ribosomal protein S18B

Gene Aliases

PTD017, S18amt, C6orf14, HSPC183, MRPS18-2, HumanS18a, MRP-S18-2

Gene ID

28973

Swiss Prot

Q9Y676

Accession Number

NP_054765

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins.

Partner Proteins

TUBGCP4; CEP250; TUBGCP3; VCP; TP53; NEDD1; UBC; PARK2; EXOSC6; EWSR1; mug82; ICT1; EBNA3B; RB1; MRPS9; MRPS26; MRPS25; MRPS35; MRPS22; UBR5; MRPS28; QARS; MYH9; KARS; HNRNPAB; FUS; CAND1; CUL3; Ybx1; NFKBIL1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

Shipping Conditions

Wet Ice

Protein Length

258

NCBI Gene Symbol

MRPS18B

NCBI GB Accession Number

MRPS18B

Host or Source

Rabbit

Protein Name

28S ribosomal protein S18b, mitochondrial

Nucleotide Accession Number

NM_014046

Peptide Sequence

SVPISPYKDEPWKYLESEEYQERYGSRPVWADYRRNHKGGVPPQRTRKTC

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