ZNF346 Antibody - C-terminal region : Biotin (ARP62606_P050-Biotin)

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.

TARBP2; SNRPG; EBNA1BP2; RRP9; PRKRA; SNORA7A; AGO3; CCDC124; NOA1; BRIX1; PHAX; HP1BP3; OLA1; STAU2; KRR1; SNRPB2; SNRPA1; PPP2CA; NCBP1; RNF2; TARDBP; ANKHD1; SIRT1; CAND1; UBC; XPO5; ILF3; EIF2AK2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.