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EEF1E1 Antibody - N-terminal region : FITC (ARP62511_P050-FITC)

Selected Variant

ARP62511_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Eukaryotic translation elongation factor 1 epsilon 1

Gene Aliases

P18, AIMP3

Gene ID

9521

Swiss Prot

O43324

Accession Number

NP_004271

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Target

This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Partner Proteins

NAT9; CALCOCO2; HUWE1; RPLP0; RPL27A; RPL26; RPL24; RPL23A; RPL21; RPL18; RPL15; RPL13; RPL7A; QARS; MARS; CCAR2; RPL36; AIMP1; IQGAP1; AIMP2; IARS; DNAJA1; HNRNPA2B1; EIF4G1; EIF2S3; EIF2S1; DARS; gag; UBC; ITGA4; RARS; KARS; EPRS; ATR; ATM

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

19kDa

Shipping Conditions

Wet Ice

Protein Length

174

NCBI Gene Symbol

EEF1E1

NCBI GB Accession Number

EEF1E1

Host or Source

Rabbit

Protein Name

Eukaryotic translation elongation factor 1 epsilon-1

Nucleotide Accession Number

NM_004280

Peptide Sequence

IPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRV

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