EEF1E1 Antibody - N-terminal region: Biotin (ARP62511_P050-Biotin)

This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

NAT9; CALCOCO2; HUWE1; RPLP0; RPL27A; RPL26; RPL24; RPL23A; RPL21; RPL18; RPL15; RPL13; RPL7A; QARS; MARS; CCAR2; RPL36; AIMP1; IQGAP1; AIMP2; IARS; DNAJA1; HNRNPA2B1; EIF4G1; EIF2S3; EIF2S1; DARS; gag; UBC; ITGA4; RARS; KARS; EPRS; ATR; ATM

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.