MRPL40 Antibody - middle region : Biotin (ARP62476_P050-Biotin)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

TFCP2; TRIM27; KRT31; NOTCH2NL; KRTAP10-3; CEP57; UPF2; MMS19; MRPL21; MRPL52; MRPL43; MRPL24; MRPL9; MRPL11; MRPL32; MRPL38; MRPS9; MRPL14; TSR1; MRPL16; MRPL50; MRPL39; ATP6V1D; MRPL51; MRPL37; MRPL2; MRPL15; MRPL42; SCFD1; ZMPSTE24; HNRNPR; MRPL19; TAP

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.