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DCTN3 Antibody - C-terminal region : HRP (ARP62445_P050-HRP)

Selected Variant

ARP62445_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Dynactin 3 (p22)

Gene Aliases

DCTN22, DCTN-22

Gene ID

11258

Swiss Prot

O75355

Accession Number

NP_001239

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.

Partner Proteins

LMNB1; FLNB; FHL2; LEO1; TNKS1BP1; NUP85; CCAR2; ACTR10; DCTN2; ACTR1A; UBC; ACTR1B; DYNLT3; ATXN1; GSK3B; Dctn3; Dctn1; Capza1; PBX2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DCTN3 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

20kDa

Shipping Conditions

Wet Ice

Protein Length

186

NCBI Gene Symbol

DCTN3

NCBI GB Accession Number

DCTN3

Host or Source

Rabbit

Protein Name

Ectonucleoside triphosphate diphosphohydrolase 3

Nucleotide Accession Number

NM_001248

Peptide Sequence

ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLC

Subunit

3

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