TSEN2 Antibody - C-terminal region : Biotin (ARP62409_P050-Biotin)
Selected Variant
ARP62409_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
TRNA splicing endonuclease 2 homolog (S. cerevisiae)
Gene Aliases
SEN2, PCH2B, SEN2L
Gene ID
80746
Swiss Prot
Q8NCE0
Accession Number
NP_079541
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Target
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
TSEN54; UBC; TBC1D2; PRPF39; POLD3; TBC1D4; TRIP10; USP8; POLD1; Clp1; RANBP10; TSEN15; TSEN34
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Pig: 93%; Rabbit: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
Shipping Conditions
Wet Ice
Protein Length
465
NCBI Gene Symbol
TSEN2
NCBI GB Accession Number
TSEN2
Host or Source
Rabbit
Protein Name
TRNA-splicing endonuclease subunit Sen2
Nucleotide Accession Number
NM_025265
Peptide Sequence
LRRPLSWKSLAALSRVSVNVSKELMLCYLIKPSTMTDKEMESPECMKRIK
Subunit
Sen2
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