EIF3D Antibody - N-terminal region : HRP (ARP62386_P050-HRP)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 3, subunit D

Gene Aliases

EIF3S7, eIF3-p66, eIF3-zeta

Gene ID

8664

Swiss Prot

O15371

Accession Number

NP_003744

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.

Partner Proteins

LZTS2; BEND5; HOMER3; SAT1; TRIM27; REL; SUMO2; SUMO3; STAU1; UBC; RNF2; RPL35; RPS28; RPS27; RPS20; RPS18; RPS12; RPS11; RPS9; RPS4X; RPL23A; HNRNPU; DDX3X; EIF3L; EIF3K; EIF3H; EIF3C; EIF3A; EIF3E; gag-pol; EIF3M; EIF3J; EIF3I; EIF3G; EIF3F; EIF3B; VCAM

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

EIF3D is supported by BioGPS gene expression data to be expressed in HT1080

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.