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Nploc4 Antibody - N-terminal region : FITC (ARP62292_P050-FITC)

Selected Variant

ARP62292_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Nuclear protein localization 4 homolog (S. cerevisiae)

Gene Aliases

Npl4, AK129375, mKIAA1499

Gene ID

217365

Swiss Prot

P60670

Accession Number

NP_001181952

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Nploc4

Target

The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.

Partner Proteins

Map3k1; Vcp; Ubc; Itpr1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

Shipping Conditions

Wet Ice

Protein Length

608

NCBI Gene Symbol

NPLOC4

NCBI GB Accession Number

Nploc4

Host or Source

Rabbit

Protein Name

Nuclear protein localization protein 4 homolog

Nucleotide Accession Number

NM_001195023

Peptide Sequence

GLKAFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLE

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