BABAM2 Antibody - C-terminal region : HRP (ARP62254_P050-HRP)
Product Specifications
Gene Name
BRISC and BRCA1 A complex member 2
Gene Aliases
BRE, BRCC4, BRCC45
Gene ID
9577
Swiss Prot
Q9NXR7
Accession Number
NP_954664
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Partner Proteins
FAM175B; UBC; BABAM1; AKAP2; TFG; OPTN; HNRNPA2B1; SUMO2; PAXIP1; MDC1; BRCA1; GRB2; UBD; GFI1B; UIMC1; BRCC3; FAM175A; NCOA3; COPS5; SUMO1; TNFRSF1A; FAS; MMS19; UGGT2; TMX3; DHRS7B; FKBP8; TTC28; ATG2A; SLC25A13; LRPPRC; USP7; SSR3; SHMT2; RPN2; PHB; UB
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Sample Type
BRE is strongly supported by BioGPS gene expression data to be expressed in A549
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
43kDa
Shipping Conditions
Wet Ice
Protein Length
383
NCBI Gene Symbol
BABAM2
NCBI GB Accession Number
BABAM2
Host or Source
Rabbit
Protein Name
BRISC and BRCA1-A complex member 2
Nucleotide Accession Number
NM_199194
Peptide Sequence
YHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFAN
Subunit
BRE
Frequently Asked Questions
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