BABAM2 Antibody - C-terminal region : Biotin (ARP62254_P050-Biotin)

Product Specifications

Gene Name

BRISC and BRCA1 A complex member 2

Gene Aliases

BRE, BRCC4, BRCC45

Gene ID

9577

Swiss Prot

Q9NXR7

Accession Number

NP_954664

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

Partner Proteins

FAM175B; UBC; BABAM1; AKAP2; TFG; OPTN; HNRNPA2B1; SUMO2; PAXIP1; MDC1; BRCA1; GRB2; UBD; GFI1B; UIMC1; BRCC3; FAM175A; NCOA3; COPS5; SUMO1; TNFRSF1A; FAS; MMS19; UGGT2; TMX3; DHRS7B; FKBP8; TTC28; ATG2A; SLC25A13; LRPPRC; USP7; SSR3; SHMT2; RPN2; PHB; UB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

BRE is strongly supported by BioGPS gene expression data to be expressed in A549

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.