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ORC3L Antibody - C-terminal region : HRP (ARP62223_P050-HRP)

Selected Variant

ARP62223_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Origin recognition complex, subunit 3

Gene Aliases

LAT, ORC3L, LATHEO

Gene ID

23595

Swiss Prot

Q9UBD5-2

Accession Number

NP_862820

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Target

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.

Partner Proteins

ORC5; ORC4; ORC1; MCM7; CDC6; MCM10; ORC6; CCNE2; CDC45; LRWD1; ORC2; APP; SUMO2; XRCC5; UBC; XRCC6; ZBP1; DBF4; ORC3; MCM5; CDK4; TERF2; BRCA1; MCM4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ORC3 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

82kDa

Shipping Conditions

Wet Ice

Protein Length

712

NCBI Gene Symbol

ORC3

NCBI GB Accession Number

ORC3

Host or Source

Rabbit

Protein Name

Origin recognition complex subunit 3

Nucleotide Accession Number

NM_181837

Peptide Sequence

VVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVA

Subunit

3

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