UACA Antibody - C-terminal region : Biotin (ARP62098_P050-Biotin)
Selected Variant
ARP62098_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Aliases
NUCLING
Gene ID
55075
Swiss Prot
Q9BZF9
Accession Number
NP_001008225
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
UACA regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. It promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. It regulates the redistribution of APAF1 into the nucleus after proapoptotic stress and down-regulates the expression of LGALS3 by inhibiting NFKB1.
Partner Proteins
KRT40; FUS; RNF2; HIF1AN; PAN2; TP63; UBC; USP48; RABEP1; STAMBP; FBXO25; NRD1; Mprip; MED14; CELSR3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 85%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
154kDa
Shipping Conditions
Wet Ice
Protein Length
1403
NCBI Gene Symbol
UACA
NCBI GB Accession Number
UACA
Host or Source
Rabbit
Protein Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Nucleotide Accession Number
NM_001008224
Peptide Sequence
TELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLA
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