Cul4b Antibody - C-terminal region : FITC (ARP62057_P050-FITC)
Selected Variant
ARP62057_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Cullin 4B
Gene Aliases
CUL-4B, AA409770, mKIAA0695, 2700050M05Rik
Gene ID
72584
Swiss Prot
A2A432
Accession Number
NP_001103612
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Target
Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Partner Proteins
Nedd8; Eed; Pou5f1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
111kDa
Shipping Conditions
Wet Ice
Protein Length
970
NCBI Gene Symbol
CUL4B
NCBI GB Accession Number
Cul4b
Host or Source
Rabbit
Protein Name
Cullin-4B
Nucleotide Accession Number
NM_001110142
Peptide Sequence
IQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYN
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