P4HA1 Antibody - middle region : HRP (ARP62016_P050-HRP)
Product Specifications
Gene Name
Prolyl 4-hydroxylase, alpha polypeptide I
Gene Aliases
P4HA
Gene ID
5033
Swiss Prot
P13674
Accession Number
NP_000908
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig
Target
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Partner Proteins
IRS4; UBC; WWOX; HDAC10; UBL4A; CFTR; CUL3; ELAVL1; CDK9; IRF7; EBNA-LP; SMN1; MYC
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
P4HA1 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
Shipping Conditions
Wet Ice
Protein Length
534
NCBI Gene Symbol
P4HA1
NCBI GB Accession Number
P4HA1
Host or Source
Rabbit
Protein Name
Prolyl 4-hydroxylase subunit alpha-1
Nucleotide Accession Number
NM_000917
Peptide Sequence
TKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKG
Subunit
Alpha-1
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