P4HA1 Antibody - middle region : Biotin (ARP62016_P050-Biotin)

Product Specifications

Gene Name

Prolyl 4-hydroxylase, alpha polypeptide I

Gene Aliases

P4HA

Gene ID

5033

Swiss Prot

P13674

Accession Number

NP_000908

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig

Target

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Partner Proteins

IRS4; UBC; WWOX; HDAC10; UBL4A; CFTR; CUL3; ELAVL1; CDK9; IRF7; EBNA-LP; SMN1; MYC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

P4HA1 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.