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KIF7 Antibody - C-terminal region : Biotin (ARP62009_P050-Biotin)

Selected Variant

ARP62009_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Kinesin family member 7

Gene Aliases

ACLS, AGBK, HLS2, JBTS12, UNQ340

Gene ID

374654

Swiss Prot

Q2M1P5

Accession Number

NP_940927.2

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human KIF7

Target

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 79%; Human: 100%; Mouse: 77%; Pig: 100%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

Shipping Conditions

Wet Ice

Protein Length

829

NCBI Gene Symbol

KIF7

NCBI GB Accession Number

KIF7

Host or Source

Rabbit

Protein Name

Kinesin-like protein KIF7

Nucleotide Accession Number

NM_198525.2

Peptide Sequence

RDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLP

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