PFKFB1 Antibody - C-terminal region : Biotin (ARP61879_P050-Biotin)
Selected Variant
ARP61879_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene Aliases
F6PK, HL2K, PFRX
Gene ID
5207
Swiss Prot
P16118
Accession Number
NP_002616
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Partner Proteins
PFKFB1; Prkaa2; PRKCA; PRKACA; APP; AKT1; MAPK3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
54kDa
Shipping Conditions
Wet Ice
Protein Length
471
NCBI Gene Symbol
PFKFB1
NCBI GB Accession Number
PFKFB1
Host or Source
Rabbit
Protein Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Nucleotide Accession Number
NM_002625
Peptide Sequence
EEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELER
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