PFKFB1 Antibody - C-terminal region: Biotin (ARP61878_P050-Biotin)
Product Specifications
Gene Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene Aliases
F6PK, HL2K, PFRX
Gene ID
5207
Swiss Prot
Q4VBA8
Accession Number
NP_002616
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Partner Proteins
PFKFB1; Prkaa2; PRKCA; PRKACA; APP; AKT1; MAPK3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
Shipping Conditions
Wet Ice
Protein Length
471
NCBI Gene Symbol
PFKFB1
Protein Name
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 EMBL AAH96078.1
Nucleotide Accession Number
NM_002625
Curated Selection
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