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PFKFB1 Antibody - C-terminal region : Biotin (ARP61878_P050-Biotin)

Selected Variant

ARP61878_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Gene Aliases

F6PK, HL2K, PFRX

Gene ID

5207

Swiss Prot

Q4VBA8

Accession Number

NP_002616

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Partner Proteins

PFKFB1; Prkaa2; PRKCA; PRKACA; APP; AKT1; MAPK3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

Shipping Conditions

Wet Ice

Protein Length

471

NCBI Gene Symbol

PFKFB1

NCBI GB Accession Number

PFKFB1

Host or Source

Rabbit

Protein Name

6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 EMBL AAH96078.1

Nucleotide Accession Number

NM_002625

Peptide Sequence

CPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDT

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