PFKP Antibody - C-terminal region : FITC (ARP61860_P050-FITC)
Product Specifications
Gene Name
Phosphofructokinase, platelet
Gene Aliases
PFKF, PFK-C, PFK-P, ATP-PFK
Gene ID
5214
Swiss Prot
Q01813
Accession Number
NP_002618
Host
Rabbit
Reactivity
Human
Target
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11) . PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
Partner Proteins
UBC; SUMO2; EGFR; rev; VAT1; TUBB4B; PPIB; PFKM; PCBP1; EEF1A1; CRYZ; HIPK4; FBXO6; MAPK4; HDAC6; SOX2; ILK; CD81; WNK1; AGO2; ITGA4; FN1; TMPO; PFKL; EPRS; COPS5; CUL3; ACD; PARD3; TINF2; FBXO25; POT1; TERF1; SIRT7; WIPI2; GBAS; DMWD; DYNLL1; MCC
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
PFKP is supported by BioGPS gene expression data to be expressed in RPMI 8226
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
85kDa
Shipping Conditions
Wet Ice
Protein Length
784
NCBI Gene Symbol
PFKP
NCBI GB Accession Number
PFKP
Host or Source
Rabbit
Protein Name
6-phosphofructokinase type C
Nucleotide Accession Number
NM_002627
Peptide Sequence
EWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHR
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