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PTPN3 Antibody - N-terminal region : FITC (ARP61812_P050-FITC)

Selected Variant

ARP61812_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Protein tyrosine phosphatase, non-receptor type 3

Gene Aliases

PTPH1, PTP-H1

Gene ID

5774

Swiss Prot

E9PGU7

Accession Number

NP_001138841

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Target

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

NXT2; ZCCHC10; DIP2A; WDR6; LMO1; AKR1C1; YWHAQ; UBE3A; VDR; GHR; YWHAG; ADAM17; YWHAB; VCP; CD247; ZAP70; SFN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

Shipping Conditions

Wet Ice

Protein Length

782

NCBI Gene Symbol

PTPN3

NCBI GB Accession Number

PTPN3

Host or Source

Rabbit

Protein Name

Tyrosine-protein phosphatase non-receptor type 3 Ensembl ENSP00000416654

Nucleotide Accession Number

NM_001145369

Peptide Sequence

ASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAF

Price

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