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VAC14 Antibody - C-terminal region : Biotin (ARP61721_P050-Biotin)

Selected Variant

ARP61721_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Vac14 homolog (S. cerevisiae)

Gene Aliases

TRX, TAX1BP2, ArPIKfyve

Gene ID

55697

Swiss Prot

Q08AM6

Accession Number

NP_060522

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns (3,5) P2. Other components of this complex are the PtdIns (3,5) P2-synthesizing enzyme PIKFYVE and the PtdIns (3,5) P2 phosphatase FIG4. VAC14 functions as an activator of PIKFYVE.

Partner Proteins

LINC00518; PIKFYVE; TCEANC; MGAT5B; C4orf33; PRR20A; PHYKPL; ACSS1; RHOXF2; PRADC1; ZNF34; LPAL2; ASB13; MTMR9; FNDC3B; NGB; SPRYD7; PELI1; PCMTD2; WDYHV1; PRR13; CD209; C11orf54; SMUG1; DDAH2; RBFOX2; SNF8; PDE4DIP; SIGLEC5; BHLHE40; TP53BP1; PPP2CA; PHF

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 79%; Rabbit: 79%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

Shipping Conditions

Wet Ice

Protein Length

781

NCBI Gene Symbol

VAC14

NCBI GB Accession Number

VAC14

Host or Source

Rabbit

Protein Name

Protein VAC14 homolog

Nucleotide Accession Number

NM_018052

Peptide Sequence

QLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQHFEKVQN

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