UBE2V1 Antibody - C-terminal region : Biotin (ARP61716_P050-Biotin)

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

UBC; TRAF6; ube2nb; UBQLN1; FAM168A; TRAF3IP2; STUB1; PARK2; TXNDC5; YWHAQ; ECHS1; YWHAZ; YWHAG; TGM2; LDHB; SFN; G6PD; IQCB1; PELI3; ULK4; POMP; UBXN7; UBE2C; AHCYL1; SSSCA1; UBE4B; TTC9C; ATP6V1G1; ATP6V1F; ZYX; UGDH; UCHL3; UBE2V2; UBE2N; UBE2D2; UBE2B

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.