EIF3A Antibody - C-terminal region : Biotin (ARP61702_P050-Biotin)

EIF3A is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

UBC; REL; TFIP11; WWP2; SUMO2; STAU1; LGR4; WWOX; EED; SHFM1; RNF2; EIF3CL; YTHDF2; LARP1; NUDT21; EIF3C; DYNC1I2; RPS26; RPS25; RPS23; RPS20; RPS18; RPS12; RPS10; RPS9; RPS3A; RPS3; FBXO6; TARDBP; EIF3D; UBD; ICAM1; CD81; RIOK2; IGSF8; BBS4; BBS1; gag-po

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.