EIF3A Antibody - C-terminal region: Biotin (ARP61702_P050-Biotin)
Product Specifications
Gene Name
Eukaryotic translation initiation factor 3, subunit A
Gene Aliases
EIF3, P167, p180, p185, TIF32, EIF3S10, eIF3-p170, eIF3-theta
Gene ID
8661
Swiss Prot
Q14152
Accession Number
NP_003741
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Target
EIF3A is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Partner Proteins
UBC; REL; TFIP11; WWP2; SUMO2; STAU1; LGR4; WWOX; EED; SHFM1; RNF2; EIF3CL; YTHDF2; LARP1; NUDT21; EIF3C; DYNC1I2; RPS26; RPS25; RPS23; RPS20; RPS18; RPS12; RPS10; RPS9; RPS3A; RPS3; FBXO6; TARDBP; EIF3D; UBD; ICAM1; CD81; RIOK2; IGSF8; BBS4; BBS1; gag-po
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that EIF3A is expressed in HeLa
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
152kDa
Shipping Conditions
Wet Ice
Protein Length
1382
NCBI Gene Symbol
EIF3A
Protein Name
Eukaryotic translation initiation factor 3 subunit A
Nucleotide Accession Number
NM_003750
Curated Selection
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