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ARHGDIB Antibody - N-terminal region : FITC (ARP61689_P050-FITC)

Selected Variant

ARP61689_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2

Gene ID

397

Swiss Prot

P52566

Accession Number

NP_001166

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGDIB

Target

Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs) . The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.

Partner Proteins

ZBTB1; Rabgef1; Rab6a; APP; UBC; UFM1; RAC3; RAC1; RAC2; RHOH; CASP3; RHOA; VAV1; EZR; CDC42; CUL3; KLHL12

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ARHGDIB is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 93%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

Shipping Conditions

Wet Ice

Protein Length

201

NCBI Gene Symbol

ARHGDIB

NCBI GB Accession Number

ARHGDIB

Host or Source

Rabbit

Protein Name

Rho GDP-dissociation inhibitor 2

Nucleotide Accession Number

NM_001175

Peptide Sequence

MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKK

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