MTNR1A Antibody - C-terminal region : Biotin (ARP61495_P050-Biotin)

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

VAPB; IRS4; RAP1A; RAC1; HSPA5; GNB1; GNAI3; GNAI2; GNAI1; GNB4; LRRC59; TMEM33; HNRNPA0; RAB10; PGRMC1; PDIA6; FLNA; EEF1G; CNP; CANX; CALR; GPR50; GNA13; DPM1; MTNR1B; MTNR1A; GNA11

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.