IRAK4 Antibody - C-terminal region : Biotin (ARP61431_P050-Biotin)
Product Specifications
Gene Name
Interleukin-1 receptor-associated kinase 4
Gene Aliases
IPD1, IMD67, REN64, IRAK-4, NY-REN-64
Gene ID
51135
Swiss Prot
Q9NWZ3-2
Accession Number
NP_001138728
Host
Rabbit
Reactivity
Human, Rat, Cow, Guinea Pig, Horse, Sheep
Target
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
MYD88; IRAK1; IKBKG; SASH1; ARNT; TNFRSF13B; IL1RL1; TRAF6; PELI1; PELI2; IL1R1; MBP; HIST1H1A; HIST1H1T; HIST1H1B; HIST1H1E; HIST1H1D; HIST1H1C; EIF4EBP1; TIRAP; IRAK3; IRAK2; TLR4; TICAM2; TBPL1; PELI3; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
IRAK4 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Cow: 77%; Guinea Pig: 91%; Horse: 92%; Human: 100%; Rat: 91%; Sheep: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-IRAK4 (ARP61431_P050-Biotin) antibody
Protein Length
336
NCBI Gene Symbol
IRAK4
NCBI GB Accession Number
IRAK4
Host or Source
Rabbit
Protein Name
Interleukin-1 receptor-associated kinase 4
Nucleotide Accession Number
NM_001145256
Peptide Sequence
TGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS
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