MUS81 Antibody - C-terminal region : Biotin (ARP61405_P050-Biotin)
Product Specifications
Gene Name
MUS81 endonuclease homolog (S. cerevisiae)
Gene Aliases
SLX3
Gene ID
80198
Swiss Prot
Q96NY9
Accession Number
NP_079404
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig
Target
MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Partner Proteins
SLX4; vpr; EME1; PLK1; FBXL5; SLX1A; WEE1; EME2; SUMO2; SLX1B; MUS81; CHEK2; TERT; TERF2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 86%; Human: 100%; Mouse: 79%; Pig: 83%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-MUS81 (ARP61405_P050-Biotin) antibody
Protein Length
551
NCBI Gene Symbol
MUS81
NCBI GB Accession Number
MUS81
Host or Source
Rabbit
Protein Name
Crossover junction endonuclease MUS81
Nucleotide Accession Number
NM_025128
Peptide Sequence
GETRGGGHRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDPANPGE
Curated Selection
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