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EIF6 Antibody - N-terminal region : FITC (ARP61388_P050-FITC)

Selected Variant

ARP61388_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Eukaryotic translation initiation factor 6

Gene Aliases

CAB, EIF3A, eIF-6, p27BBP, ITGB4BP, b (2) gcn, p27 (BBP)

Gene ID

3692

Swiss Prot

P56537

Accession Number

NP_002203

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Target

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.

Partner Proteins

ZNF622; BCCIP; PPAN; NMD3; GLTSCR2; GTPBP4; POP1; TOP2B; TOP2A; RNF2; CNBP; RARS; PPP5C; PEPD; PAFAH1B2; HSPA9; HSPA1A; HPRT1; EIF4E; DFFA; CFL1; CAPN1; ASNA1; GINS3; BZW2; ABHD14A; TNFAIP8; XRN2; HDAC9; ZBTB26; VCAM1; UBC; ECT2; HNRNPU; FBL; DHX9; APP; R

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

EIF6 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%; Yeast: 85%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Protein Length

245

NCBI Gene Symbol

EIF6

NCBI GB Accession Number

EIF6

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 6

Nucleotide Accession Number

NM_002212

Peptide Sequence

AVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHA

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