EIF6 Antibody - N-terminal region: FITC (ARP61388_P050-FITC)
Product Specifications
Gene Name
Eukaryotic translation initiation factor 6
Gene Aliases
CAB, EIF3A, eIF-6, p27BBP, ITGB4BP, b (2) gcn, p27 (BBP)
Gene ID
3692
Swiss Prot
P56537
Accession Number
NP_002203
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Target
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.
Partner Proteins
ZNF622; BCCIP; PPAN; NMD3; GLTSCR2; GTPBP4; POP1; TOP2B; TOP2A; RNF2; CNBP; RARS; PPP5C; PEPD; PAFAH1B2; HSPA9; HSPA1A; HPRT1; EIF4E; DFFA; CFL1; CAPN1; ASNA1; GINS3; BZW2; ABHD14A; TNFAIP8; XRN2; HDAC9; ZBTB26; VCAM1; UBC; ECT2; HNRNPU; FBL; DHX9; APP; R
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
EIF6 is supported by BioGPS gene expression data to be expressed in 721_B, HeLa
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%; Yeast: 85%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
245
NCBI Gene Symbol
EIF6
Protein Name
Eukaryotic translation initiation factor 6
Nucleotide Accession Number
NM_002212
Curated Selection
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