H2AFZ Antibody - C-terminal region : Biotin (ARP61353_P050-Biotin)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

UBC; ASB9; ASB16; WWOX; ZBTB1; OGFOD1; TRNT1; ACAA2; NOL3; EZR; PYGL; PSMD9; FH; UBD; PAN2; HIST1H3B; CENPA; MAGEC1; SUMO1; SUMO3; NEDD8; EPC1; MEAF6; ACTR6; EP400; DMAP1; MRGBP; ING3; MORF4L1; RUVBL2; SRCAP; KAT5; RUVBL1; TRRAP; YEATS4; VPS72; ACTL6A; HI

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.