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TNFAIP3 Antibody : FITC (ARP61326_P050-FITC)

Selected Variant

ARP61326_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Tumor necrosis factor, alpha-induced protein 3

Gene Aliases

A20, AISBL, OTUD7C, TNFA1P2

Gene ID

7128

Swiss Prot

P21580

Accession Number

NP_006281

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP

Target

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF) . The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Partner Proteins

YWHAQ; TNIP1; TNIP3; ARRDC3; RNF114; UBE2D1; UBC; TRAF2; TNFAIP3; TRIM23; ELAVL1; MALT1; OCLN; TP53; BIRC3; BIRC2; NFKB2; AXIN1; GIT2; IKBKG; LAPTM5; YWHAZ; YWHAE; RNF11; HSP90AA1; RNF5; RLIM; TRIM2; RBCK1; TRIM3; RNF14; TRIM5; TRIM8; TRAF6; SHARPIN; RNF3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 77%; Horse: 85%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

90 kDa

Shipping Conditions

Wet Ice

Protein Length

790

NCBI Gene Symbol

TNFAIP3

NCBI GB Accession Number

TNFAIP3

Host or Source

Rabbit

Protein Name

Tumor necrosis factor alpha-induced protein 3

Nucleotide Accession Number

NM_001270507

Peptide Sequence

LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP

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