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SFRS2 Antibody - C-terminal region : Biotin (ARP61320_P050-Biotin)

Selected Variant

ARP61320_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Serine/arginine-rich splicing factor 2

Gene Aliases

SC35, PR264, SC-35, SFRS2, SFRS2A, SRp30b

Gene ID

6427

Swiss Prot

Q01130

Accession Number

NP_003007

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish

Target

The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.

Partner Proteins

KRT40; LZTS2; CEP72; HUWE1; TCF4; TRIM27; KRT31; GOLGA2; EED; PARK2; SRPK2; SRPK1; YWHAE; CIR1; UBC; U2AF1; TRA2B; SRSF4; SRSF3; SRSF2; CSNK2A1; CDK6; EIF4A3; MAGOH; PAXIP1; LIG4; ESR1; BARD1; NUBP2; UBA2; HNRNPDL; ATP6V1F; RUVBL1; XPO1; UBE2B; TTN; TPM4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SRSF2 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

Shipping Conditions

Wet Ice

Protein Length

221

NCBI Gene Symbol

SRSF2

NCBI GB Accession Number

SRSF2

Host or Source

Rabbit

Protein Name

Serine/arginine-rich splicing factor 2

Nucleotide Accession Number

NM_003016

Peptide Sequence

KSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAV

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