RCC1 Antibody - C-terminal region : FITC (ARP61300_P050-FITC)
Selected Variant
ARP61300_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Regulator of chromosome condensation 1
Gene Aliases
CHC1, RCC1-I, SNHG3-RCC1
Gene ID
1104
Swiss Prot
P18754
Accession Number
NP_001260
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Partner Proteins
UBC; SUMO2; SUMO1; NEDD8; MDM2; SUZ12; RNF2; PTMA; HDAC9; HMGA1; VCAM1; ITGA4; FN1; U2AF1; RANBP1; RAN; HNRNPM; HNRNPK; LUC7L3; SF3B6; NCSTN; ACIN1; RBM14; HDGF; SPRED1; FLAD1; WIZ; LRIF1; CSAD; SDF4; TRMT2A; DDAH2; FAF1; NUDT21; CCT7; TUBB3; CDK2AP2; KMT
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
Shipping Conditions
Wet Ice
Protein Length
421
NCBI Gene Symbol
RCC1
NCBI GB Accession Number
RCC1
Host or Source
Rabbit
Protein Name
Regulator of chromosome condensation
Nucleotide Accession Number
NM_001269
Peptide Sequence
AWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKD
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