RCC1 Antibody - C-terminal region : Biotin (ARP61300_P050-Biotin)
Product Specifications
Gene Name
Regulator of chromosome condensation 1
Gene Aliases
CHC1, RCC1-I, SNHG3-RCC1
Gene ID
1104
Swiss Prot
P18754
Accession Number
NP_001260
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Partner Proteins
UBC; SUMO2; SUMO1; NEDD8; MDM2; SUZ12; RNF2; PTMA; HDAC9; HMGA1; VCAM1; ITGA4; FN1; U2AF1; RANBP1; RAN; HNRNPM; HNRNPK; LUC7L3; SF3B6; NCSTN; ACIN1; RBM14; HDGF; SPRED1; FLAD1; WIZ; LRIF1; CSAD; SDF4; TRMT2A; DDAH2; FAF1; NUDT21; CCT7; TUBB3; CDK2AP2; KMT
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-RCC1 (ARP61300_P050-Biotin) antibody
Protein Length
421
NCBI Gene Symbol
RCC1
NCBI GB Accession Number
RCC1
Host or Source
Rabbit
Protein Name
Regulator of chromosome condensation
Nucleotide Accession Number
NM_001269
Peptide Sequence
AWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKD
Curated Selection
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