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XRCC3 Antibody - middle region : FITC (ARP61275_P050-FITC)

Selected Variant

ARP61275_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Gene Aliases

CMM6

Gene ID

7517

Swiss Prot

O43542

Accession Number

NP_005423

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Guinea Pig

Target

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Partner Proteins

SWSAP1; ZSWIM7; UBC; FANCG; BRCA2; ZNHIT3; RAD51D; RAD51C; RAD51

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

346

NCBI Gene Symbol

XRCC3

NCBI GB Accession Number

XRCC3

Host or Source

Rabbit

Protein Name

DNA repair protein XRCC3

Nucleotide Accession Number

NM_005432

Peptide Sequence

LAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQ

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