XRCC3 Antibody - C-terminal region : Biotin (ARP61274_P050-Biotin)
Selected Variant
ARP61274_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
X-ray repair complementing defective repair in Chinese hamster cells 3
Gene Aliases
CMM6
Gene ID
7517
Swiss Prot
O43542
Accession Number
NP_005423
Host
Rabbit
Reactivity
Human, Dog, Rabbit
Target
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Partner Proteins
SWSAP1; ZSWIM7; UBC; FANCG; BRCA2; ZNHIT3; RAD51D; RAD51C; RAD51
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
XRCC3 is supported by BioGPS gene expression data to be expressed in MCF7
Concentration
0.5 mg/ml
Homology
Dog: 92%; Human: 100%; Rabbit: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
38kDa
Shipping Conditions
Wet Ice
Protein Length
346
NCBI Gene Symbol
XRCC3
NCBI GB Accession Number
XRCC3
Host or Source
Rabbit
Protein Name
DNA repair protein XRCC3
Nucleotide Accession Number
NM_005432
Peptide Sequence
LADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH
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