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CAMK2B Antibody - C-terminal region: HRP (ARP61268_P050-HRP)

Product Specifications

Gene Name

Calcium/calmodulin-dependent protein kinase II beta

Gene Aliases

CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta

Gene ID

816

Swiss Prot

Q53H78

Accession Number

NP_742075

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B

Target

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.

Partner Proteins

KRTAP10-11; KRTAP19-7; KRTAP19-5; FAM171A2; MGAT5B; CCM2L; TTC5; AP5B1; MRPL11; SEMA4G; SPRYD7; MED18; POP5; RBFOX2; ACOT7; RBPMS; MORF4L1; MAD2L2; RPL11; RAP2B; PHKB; CAMK2B; MVP; SMYD3; UBC; ATXN1; HSP90AA1; Rad23a; THRB; RXRG; YWHAB; CAMK2N2; CAMK2D; A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

Shipping Conditions

Wet Ice

Protein Length

542

NCBI Gene Symbol

CAMK2B

Protein Name

Calcium/calmodulin-dependent protein kinase IIB isoform 2 variant EMBL BAD96423.1

Nucleotide Accession Number

NM_172078

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