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DHPS Antibody - N-terminal region : Biotin (ARP61225_P050-Biotin)

Product Specifications

Gene Name

Deoxyhypusine synthase

Gene Aliases

DS, DHS, MIG13, NEDSSWI

Gene ID

1725

Swiss Prot

P49366

Accession Number

NP_037538

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DHPS

Target

This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

ZNF138; RPL9; REL; RAB27B; PTPRH; EIF5A; DHPS; EIF5A2; WDYHV1; VASH1; MAPK3; ANKMY2; CTPS2; DPP8; ARIH1; ANP32B; PLIN3; ACTR2; ARPC1B; SAE1; SURF2; SRP9; RPA3; PPP2R5D; HSF1; HNRNPF; AAMP; NUDT18; NIF3L1; UBC; SRRM2; ARF6

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DHPS is strongly supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-DHPS (ARP61225_P050-Biotin) antibody

Protein Length

322

NCBI Gene Symbol

DHPS

NCBI GB Accession Number

DHPS

Host or Source

Rabbit

Protein Name

Deoxyhypusine synthase

Nucleotide Accession Number

NM_013406

Peptide Sequence

TTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIF

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