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VASP Antibody - middle region : FITC (ARP61210_P050-FITC)

Selected Variant

ARP61210_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Vasodilator-stimulated phosphoprotein

Gene ID

7408

Swiss Prot

P50552

Accession Number

NP_003361

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human VASP

Target

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Partner Proteins

ABI3; FGFR1OP; ABI2; SCGB2A2; CEP250; TP53; XIRP1; UBC; FAT1; FOXK1; PPP4R2; PAAF1; PRPF40A; RPP38; PRMT5; POP7; CUL4B; PSMA5; DDB1; APBB1; YWHAQ; NR4A1; YWHAE; DMRTB1; NPM1; VCAM1; SAT1; ITGA4; FN1; AMOT; SF3B2; SF3A3; ATP6V1F; CPNE3; SRSF9; UBE2N; UAP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 90%; Human: 100%; Mouse: 91%; Rabbit: 92%; Rat: 92%; Yeast: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

380

NCBI Gene Symbol

VASP

NCBI GB Accession Number

VASP

Host or Source

Rabbit

Protein Name

Vasodilator-stimulated phosphoprotein

Nucleotide Accession Number

NM_003370

Peptide Sequence

WSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGP

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